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PK parameter estimations were computed from individual plasma concentrations applying a non-compartmental approach using appropriate validated PK software (Phoenix Copyright 2012, Pharsight Corporation, St Louis, MO, USA).
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The inertial effects of the system are approached using appropriate lumped masses in atomic positions.
Therefore, we are convinced that elucidating similar aspects of biological alterations in animal models and human patients can be a major progress and that translational approaches using appropriate animal models can substantially further our understanding of how organisms respond to stress and the nature of inter-individual differences in the stress response.
All mutant constructs were generated using PCR-based approaches using appropriate primers or site-directed mutagenesis.
Obviously, this hypothesis has to be tested in the future by metabolomic approaches using appropriate collections of accessions from both species.
The confidence intervals for prevalence ratio using logistic regression should be defined using appropriate approaches, such as delta and bootstrap methods.
Greater knowledge about insulin pharmacokinetics and using appropriate approaches to minimize exercise-induced hypoglycemia were factors associated with fewer perceived barriers.
The significance of predictive genetic markers from high-dimensional data will be assessed in Cox regression models using appropriate approaches, such as boosting or permutation tests with potential confounders being included as covariates.
The biological functions of predicted genes have to be validated by further studies using appropriate approaches such as insertional mutagenesis, serial analysis of gene expression, microarray analysis, proteomics, and metabolomics.
[Tina, daughter of Eric]." Quality of care was judged in terms of food, hydration, maintaining safety, showing warmth towards patient and family carer, using appropriate approaches to caring for a confused person, and suitable medical care.
The study highlights considerations relevant to health impact and epidemiologic applications, including the importance of selecting appropriate pollutants, using appropriate monitoring approaches, considering prevailing wind directions during study design, and accounting for uncertainty.
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