Sentence examples for approach to inactivate from inspiring English sources

It is likely that RNAi technique is a good therapeutic approach to inactivate PKC gene and to normalize vascular functions and high arterial blood pressure in SHR.

Targeted cleavage of mRNA by RNase P using EGSs provides a unique approach to inactivate any RNA of known sequence expressed in vivo.

In one set of experiments, we took advantage of a mutation that specifically disrupts the function of the ChOs while a second set of experiments used a combinatorial misexpression approach to inactivate the majority of sensory neurons in the leg, including the ChO, hair plates, campaniform sensilla and mechanosensory bristles.

The most interesting aspect of the work involves inactivating sensory neurons of the legs; one set of experiments uses a mutation that specifically disrupts the function of chrodotonal organs, while a second set of experiments uses a combinatorial misexpression approach to inactivate the majority of sensory neurons in the leg.

The present study represents the first genetic approach to inactivate CAP1/ Prss8 gene inactivation in a Na+-transporting epithelium.

Although Casodex and MDV3100 are known as specific AR antagonists [ 54- 57], and the TIF response appears to be due to AR inactivation (Fig. 1B), we tested the effect of androgen depletion as an alternative approach to inactivate AR.

As MLN4924 treatment only results in transient inhibition of NAE, we next verified our results using two genetic approaches to inactivate the enzyme.

Thus three independent approaches to inactivating ceramide, bFGF/VEGF inactivation of ASMase translocation, nystatin disruption of GE Ms,and binding ceramide on the cell surface with an anti-ceramide antibody, all show ceramide signaling is critical to the pro-apoptogenic effect of DC101.

It could be due to the different model systems used in these studies, or the different approaches used to inactivate or remove the myosin head domain.

To test whether the chromatin-condensing activity of CENP-V requires its putative catalytic site, we used a site-directed mutagenesis approach to specifically inactivate the putative enzyme function of CENP-V.

Previously, a different approach was used to inactivate PPO genes in apples and potatoes.