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The CDU has and continues to apply a phased approach to enrolling healthcare facilities.
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We use a three stage approach to enroll study participants.
With assistance from the staff of the National Center for Health Statistics at the Centers for Disease Control and Prevention, NCS staff developed a multistage clustered sampling approach to enroll a sample of 100,000 live births representative of all American children (Strauss et al. 2004).
The design of the NCS has been extensively described elsewhere, especially focusing on the multistage clustered sampling approach to enroll a sample of 100,000 live births representative of all American children (Branum et al. 2003; Landrigan et al. 2006; Trasande and Landrigan 2004; Trasande et al. 2006).
This study used in-depth qualitative interviews with parents who were approached to enroll their children in a clinical trial in order to gain an understanding of the barriers to pediatric clinical trial participation.
For the control group, 188 rural residents (assumed to be households) from a county with low animal density based on 1992 agriculture census data were approached to enroll.
Six hundred and six consecutive, pregnant, HIV-infected women were approached to enroll in the study within the IDI antenatal clinic.
Of the 407 women approached to enroll in the study, 396 consented and 11 refused to give consent for various reasons.
All women with a biopsy confirming breast cancer at Galway Hospital and its affiliates are approached to enroll in the breast cancer study including DNA collection.
If the medical team determined that patients were making their own medical decisions and were not delirious, then patients were approached to enroll in the study.
If patients were disoriented or were assessed not to be making their own medical decisions, then the patients' surrogate decision makers (as named by the medical team) were approached to enroll in the study.
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