Sentence examples for approach to compound from inspiring English sources

Once sufficient and adequately validated data are available, toxicogenomics can become part of a hierarchical approach to compound assessment.

This study provides a resource for the development of inhibitors against numerous disease-associated mutant kinases and illustrates the potential of unbiased profiling as an approach to compound-centric inhibitor development.

This paper presents a first-generation approach to compounds with branched or "split" pony tails of the formula (CH2 lCH[(CH2)mRfn]2. Allyl tri n-butyl tin is reactri n-butyl tinperfluorooctyl isdide (reactedirstwiceotochemical, 78–81%; second, thermal with radical initiator, 71%; 13–18 g scales) to give the secondary alkyl iodide ICH(CH2Rf8)2 (3).

To the medicinal chemist they offer new, usually untapped disconnection approaches to compounds of interest.

Thus, the CIIT is applying toxicogenomics and systems biology approaches to compounds such as formaldehyde and chloroform in order to more fully elucidate cancer mechanisms and potentially demonstrate nonlinearity of cancer dose responses.

While such a probabilistic approach only works for SARMs, which are sufficiently populated and have shared substitution pattern, the approach is not restricted to compound subsets representing continuous SAR only.

This requires model systems that can recapitulate key features of human neurodegenerative diseases that are also amenable to compound screening approaches.

Ratliff's unusual approach to the compound difficulties of writing about Coltrane is not to rehearse the story of his life but to trace the history of his sound.

Similarity-measure-based spectrum matching is an effective approach to chemical compound identification.

Overall, this study shows that this conformal gain-cost driven method is a promising approach to optimize compound selection in screening programs in terms of optimising the gain.

Therefore, to minimize its interference on the chemical behavior of the rest of the molecule, the side chain to be hidden was an appropriate approach to synthesize compound 10.