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Overall, the pattern of marker distribution on chromosomes observed for our population also has good agreement with that of reference map, indicating the potential of POPSEQ approach of marker ordering and imputing.
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In the absence of the analyte cation, electrostatic repulsion between the marker anions and the carboxylate groups of the receptor monolayer hindered the approach of the marker anion to the electrode surface and hence hindered its reduction.
Meeting clinical action measures rather than the treat-to-target approach of surrogate markers is now more and more recommended to improve appropriateness of care [ 3, 8, 14].
The latter would benefit from full consideration of all information already available for a PSH, and a parallel, combined approach of multiple markers and multiple delimitation methods.
We demonstrated the feasibility of the BSTA approach for marker enrichment and fine-mapping of specific genomic regions in a non-model organism.
For both approaches, the resolution of marker order conflicts was informed by weighting input maps in proportion to the average GIC of the markers contained in each map.
This epidemiologic investigation took advantage of the TMA approach that allows assessment of marker expression in a large number of pathologic samples under similar staining conditions [ 34, 42].
The only conventional cardiac biomarker that could approach the early presence of marker levels above normal ranges is myoglobin, whose levels begin to rise 1 h after myocardial injury [ 3].
We believe that our approach of first identifying markers expressed by different muscle populations based on their anatomic position and applying this knowledge to separate the cell populations by flow cytometry will be useful to understand the relationship of "bonafide" endothelial cells with endothelial precursor cells or multipotent cells of the skeletal muscle.
Beyond the classic approach of using visible markers, two basic approaches can be taken to define the landscape of meiotic recombination with high resolution.
Iterative approaches of adding markers to a framework map, akin to the method used in this analysis, are commonly employed [ 139- 142].
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