Sentence examples for approach of candidate from inspiring English sources

A disadvantage of the hypothesis-based approach of candidate gene studies is that genes involved in the pathogenesis of a disease through unknown pathways are overlooked.

Interestingly, the association of rs1047891 to glycine was also previously reported by Shin et al. (23) using a fine-mapping approach of candidate loci based on 1000 Genomes Project data imputed genetic variants [see the Supplementary Material, Table S8 in Shin et al. (23)].

The closest distance between outlier SNPs was 9000 bp in scaffold 1, 19,000 bp in scaffold 21 but around 125,000 bp in scaffold 3. We examined the patterns of genomic diversity across life cycle stages in European eel, using a combined approach of candidate coding-gene SNPs and a large-scale genomic analysis of 153,423 SNPs generated by RAD sequencing.

The approach of proposing candidate genes in the vicinity of the peak location within a selection signature represents a common way to identify a possible candidate gene (e.g. [ 10]).

In addition to the breeding approaches, overexpression of candidate genes and upstream transcriptional regulators has been widely used to introduce tolerance against abiotic stresses [ 6].

Experts say the get-tough approach of both candidates highlights how desperate Guatemalans have become in the face of spiraling insecurity.

Mr. Trump's willingness to say just about anything, and his merry courting of trouble, was an eye-opening break from the traditional, tightly scripted approach of keeping candidates away from trouble.

As for her own prospects in Holborn and St Pancras, she has the typical underdog approach of Parliamentary candidates up and down the country, insisting she and her team is working "very hard to be MP" and "we'll see what happens".

The approach requires assignment of candidate cell types to candidate genes and identifies potentially causal (non-coding) SNPs at which variation is predicted to influence transcription factor binding.

Integrative analysis of this knowledge in the context of disease mechanism is a promising approach towards identification of candidate biomarkers taking into consideration the complex etiology of disease.

Coupling measurements of deconstructive activity with comparative analyses to identify overexpressed enzymes in lignocellulolytic communities provides a targeted approach for discovery of candidate enzymes for more efficient biomass deconstruction.