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We note that our approach (manual parameters or classifiers) is the only one which is able to detect all of the events.
Our first approach (manual quantification) requires only visual inspection of treated and control larvae and can thus be carried out using low-power magnification.
In the first approach manual segmentations by two observers of six T1w datasets (the PDw dataset is implicitly segmented after rigid registration to the T1w datasets), that include labels for GM, WM, CSF, and BG, were used as training data [ 30, 40].
Other factors that can affect quantification of heterogeneity include image artefacts, co-registration for longitudinal and histologic studies, the anatomic level at which tumour is delineated (whole tumour volume, largest cross-section or size of the subregions), the extent of which depends on the segmentation approach (manual, semi-automated or automated).
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The designs theorized for the micro channels were simulated using two approaches; manual, macro-scale calculations and CFD micro-fluidic simulation.
Approaching Manual Puig's Kiss of the Spider Woman, the pair surrounded a harsh environment--this time Argentina's political prisoners--with songs reflecting wryly on the focal plight.
Furthermore, in the aforementioned approaches manual curation and/or incorporation of the external knowledge are employed.
Among conservative approaches, manual therapy, including spinal manipulation therapy (SMT) as well as mobilization, has been suggested to be an appropriated therapeutic option in the treatment of both acute and chronic LBP [ 7, 9].
PsN currently incorporates several binning approaches: manual bin specification (-bin_array=x,y,z,etc), binning into an equal number of data points per bin (-bin_by_count=1 –no_of_bins=#), or spacing the bins equally over the x-axis (-bin_by_count=0, -no_of_bins=#).
10 18 Several other studies have looked at a less pragmatic approach to manual therapy by breaking down the manual therapy approach into several subcomponents.
The quasi-manual approach requires more manual effort to develop a new service, whereas the pattern-based one requires a more elaborate design and a more powerful tool, in order to help service creators.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com