Sentence examples for approach is substantial from inspiring English sources
A number of bondholders expect Greek bond yields to trade more in line with those of Portugal in the coming years, but without the prospect of a future buyback to push up the prices of Greek government bonds, the risk to such an approach is substantial.
Women with locally advanced vulvar carcinoma have an excellent chance of a cure by undergoing a radical vulvectomy with an "en bloc" inguinofemoral lymphadenectomy, but the morbidity associated this surgical approach is substantial.
The potential impact on preoperative resource requirements of such an approach is substantial.
As we have discussed, a major challenge in this quest is to ascertain that the source fluid derives from the interstitial fluid, but if we can, the potential of such an approach is substantial.
The cost difference between a biologically targeted and a national coverage approach is substantial, at least 55 million United States dollars (US$) for commodities alone, assuming the current price of about 5 US$ per LLIN, highlighting the benefits of a more effective spatial targeting of intervention delivery based on existing coverage, malaria risk and population settlement.
The discrepancies between the two coding approaches are substantial.
One important advantage of the GEE approach is a substantial reduction in the amount of missing data.
We recognize that our AIC approach is a substantial departure from methods long used in empirical criminology.
Leonard et al. (1997) have pointed out, by reviewing studies on the factorial approach validated by DLW and HR methods, that underestimation with the factorial approach is more substantial at moderate to high activity levels than at very low activity levels.
Given the nature of the BCB of Rickettsiales and mitochondrial genomes, and the ability of the CAT model to accommodate saturation due to convergences and reversions (Lartillot et al. 2007), this approach is of substantial importance for estimating Rickettsiales phylogeny (Rodriguez-Ezpeleta and Embley 2012; Viklund et al. 2012).
A retrospective carbon dating approach proves that there is substantial production of new neurons in the adult human brain throughout life.
