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Additional compounds are in earlier stages of development, and the future of this approach in solid tumours is promising.
Common NKLR recognition patterns of tumors, as demonstrated here in melanoma, would allow implementation of this approach in solid malignancies and potentially in hematological malignancies, either independently or in adjunction to other modalities.
The STEM PACE study will evaluate the role of allo-HSCT using a novel approach in solid tumors.
The tissue-based concepts postulate that transformed cells are not completely autonomous but can be affected by signals from stromal cells., However, although there seems to be evidence for the tissue-based approach in solid tumors, there is no new concept for the molecular mechanism of the malignant transformation of cancer cells.
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Consequently, the book is addressed to all those who want to get an overview of new approaches in solid biomass usage for heat, power, and fuel production.
The analytical approaches, in solid-state NMR technique, are based on 1H 1H and 1H 13C dipolar nuclear interactions and structural mobility, which largely determine the signal behavior in cross polarization experiments [15].
One such method is the ballistic approach, in which solid vaccine particles or vaccine-coated gold particles are accelerated towards the skin by needle-free devices, so that the particles are deposited in the epidermal and dermal layers of the skin.
Radiochemotherapy is a standard approach in advanced solid human tumors.
The most effective approach in many solid malignancies has been to interfere with VEGF-mediated blood vessel recruitment to tumour tissue.
An alternative approach used extensively in solid mechanics, also known to alleviate locking, is the class of multi-field variational principles, which gained popularity with the pioneering work of Herrmann on isotropic linear elasticity [38].
As outlined in the paragraphs above, both reversible and irreversible electroporation are promising approaches in treating solid tumors, however their success is highly dependent on local field strength.
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