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The government push is adding momentum to an approach in progress for several years among universities and medical centers that have been testing companies' drugs and devices.
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Taken together, these data indicate that although the causal variants in the 16p13 region lie within CLEC16A, DEXI is an unappreciated autoimmune disease candidate gene, and illustrate the power of the 3C approach in progressing from genome-wide association studies results to candidate causal genes.
This strategy of basal insulin to control fasting BG first and, if needed, followed by an additional single prandial insulin injection ("basal plus" concept) offers a simple, stepwise approach in progressing from a basal insulin to a basal-bolus regimen (37, 38).
Investigational approaches in progress explore whether the outcome of patients with mediastinal primary GCT can be further improved with the use of first-line sequential HD-CT or with the addition of further active drugs to the HD-VIP regimen (Hartmann et al, 2001c).
A large randomized clinical study to test the described approach is in progress.
Studies on isolating bioactive compounds using bioassay guided approach are in progress.
At present, such an approach is in progress under the umbrella of EuDial.
In fact, the approach is in progress because the actual diversity of clan AA cannot be realistically determined in a single study.
For our problem, formula (6) would be changed to where ω k reflects the "quality" of a GF k (developing this approach is in progress).
It has been suggested that MPS might be used to screen for CHD in high-risk asymptomatic diabetics, and a multicentre clinical trial to evaluate the effectiveness of this approach is in progress [ 186].
High affinity binding by IL-18 binding protein a and c isoforms renders these obvious neutralising agents, and early clinical studies to establish the safety of this approach are in progress.
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