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Using this approach has identified two lead PET compounds, 18F-SIG343 and 18F-SIG353.
This approach has identified 2-aminopyridine-3-carbonitriles as the first multi-target ligands at A1R, A2AR and PDE10A, by showing agreement between the ligand and structure based predictions at these targets.
This approach has identified a number of differences in innate and acquired immunity between susceptible and resistant strains [8] [18].
Therefore, the CHAMBER approach has identified the main effect of this genotype that was also identified by a standard analytical approach.
The CRA approach has identified a subset of parameters for the Arabidopsis clock models that prove to be consistently sensitive for multiple parameter sets.
This discussion indicates that our approach has identified many potential gene markers that are also shown to be associated with the respective cancer types in different existing studies.
Immunoscreening of cDNA expression libraries using a phage display approach has identified several tick salivary proteins that react with tick-immune serum [22], [23].
In conclusion, this approach has identified a novel target of SXL, has provided an additional potential target, and can be extended to numerous other RNA-binding proteins for which binding sites have been identified.
Our approach has identified ten candidate genes, most of which are involved in spindle checkpoint and chromosomal stability (Bub1b, Casc5, and Bub1), DNA repair (Recc1 and Prkdc) or inflammation (Duox2, Itgb2l and Cxcl5; Table 5).
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A recent study using a combined bioinformatic and high-throughput experimental approach have identified 53 miRNAs not conserved beyond primates[ 10].
Work from a number of groups, using a variety of experimental approaches, has identified some of the transcription factors that mediate photoreceptor gene expression.
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