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Adoptive T cell therapy, in which autologous cells from the patient are expanded ex vivo and reintroduced into the patient, represents a promising approach for activating the immune response against cancer [1], [2].
In this work, we describe an approach for activating a steroid-receptor in order to achieve high temporal and spatial precision and to measure the activity of a responsive gene in the same cell over time.
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Taken together, these data demonstrate the ability of nanotechnology to improve conventional approaches for activating latent HIV.
This approach could be useful for activating silenced tumor suppressors in antineoplastic therapy, controlling stem-cell differentiation and stimulating tissue regeneration.
Though useful for addressing questions depending on precise timing of transgene expression, the main caveat of this approach is that concentrations of estrogen homologues required for activating Cre approach those that affect dendritic growth and spine morphology [27].
Taken together these data demonstrate the ability of nanotechnological approaches to provide improved methods for activating latent HIV and provide key proof-of-principle experiments showing how novel delivery systems may enhance future HIV therapy.
This approach offers the possibility of global administration of ligand for activating populations of heterologously transfected neurons.
Start (for activating the master server).
It's great for activating leavening agents in baking.
A local modelling approach for these strongly activating features would likely produce better predictions for these regions of chemical space although more data will still likely be required.
An alternative approach to activating sirtuins, which raises the activity of the entire family of enzymes, is to exploit their common requirement for NAD+.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com