Very effective alternative approaches, devised in order to improve both the aptamer activity and stability, were based on the design of polyvalent aptamers, able to establish multivalent interactions with the target: thus, multiple copies of an aptamer can be assembled on the same molecular- or nanomaterial-based scaffold.
Recent computer-planning developments in radiotherapy techniques offer major advantages over the traditional opposed-field approaches devised in the 1960s, with the potential to reduce normal tissue toxicity (Dobelbower et al, 1980; Chu et al, 1992).
But Siri abandoned that method in favor of a breakthrough approach devised by Cheyer and his colleagues.
To prepare metaparticles, we instead adopted an approach devised to build finite clusters of identical particles, modified in such a way that different monomer types can be incorporated.
Later, a new approach was devised, in which multiple bad measurements were identified and removed at the same time, thus substantially reducing the SE execution time [4].
The shape sensitivity function is derived and a computational procedure based on a least squares interpolation approach is devised in order to compute sensitivities at the boundaries.
A four pronged approach was devised in an effort to take stock of what publicly-accessible datasets are available in the MENA region.
Both "in vitro" and "in vivo" approaches were devised in an attempt to draw a pattern of risk related to human consumption of fish products.
In order to determine the relevance of a concept, several effective approaches have been devised in the area of information retrieval, e.g., document frequency (Joho and Sanderson 2007) and term frequency-inverted document frequency (Baeza-Yates and Ribeiro-Neto 1999).
In her honor he created the Ramamani Iyengar Memorial Institute, which still teaches the unique approach to yoga he devised in those years of frailty and solitary practice.
