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Rather than sequence the genome piece by piece as was done for the Human Genome Project, the team took the whole-genome shotgun approach, chopping the entire genome into millions of overlapping bits for sequencing.
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In essence, the approach chops an oligomer in two and sends both halves out to find the target sequence.
Finally, the last two steps are similar since they both attempt to remove the inflectional variations of the words by using two different approaches, one approach just chops the word using heuristics (stemming) and the other approach uses a dictionary (lemmatization) in order to remove the inflections.
The European approach involves chopping the tree down.
Another perennial favorite is Malaysian-style crab, a riff on the Southeast Asian approach of chopping crabs into large pieces, sautéing them with chiles and spices, and letting the eater pry out the meat.
RNAz uses a sliding window based approach which chop out sections (typically of 120 nt) of multiple (sequence) alignments and measure the structure potential over a background in that window.
It extends the molecular beam chopping approach to fast flow systems, exploits higher reactant and product fluxes, and permits transient rate measurements of fast surface reactions at much higher pressure.
Applied Biosystems approach works by chopping the genome up into 200 million pieces that are each about 1,500 DNA base pairs long, and then sequencing just the 25 base pairs at the edges of these pieces, yielding pairs of mated tags.
As she and dance partner Derek approach the chopping block - I mean, judges' panel - host Tom Bergeron jokes that he is dedicating his hosting tonight to everybody at Riker's Island.
Physical mapping, as the Human Genome Project approach is known, relies on chopping genetic material into pieces, and working out the order of the nucleotide bases (the chemical "letters" in which the genetic message is spelled out) of each piece.
A debate ensues over what to do next, and as we dither, I make out the chopping blows of approaching footsteps.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com