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Evaluation of intoxication severity should rely on a rigorous approach based on analysis of prognostic factors.
Let us note that the known bounds (1.19)–(1.21) are the best possible in the framework of an approach based on analysis of the variance, usage of exponential functions, and of an inequality of Hoeffding (see (3.3)), which allows to reduce the problem to estimation of tail probabilities for sums of independent random variables.
We used a rational design approach based on analysis of combinatorial peptide mixtures and focused compound libraries to develop novel peptide hydroxamic acid inhibitors of IDE.
This work was carried out by employing a classical computational genomics approach based on analysis of protein sequences and structures.
They concluded that the existing evidence is limited and suggested an approach based on analysis of the mechanisms of adverse reactions and their clinical features.
Furthermore, an approach based on analysis of DNA methylation in HCC, gene reexpression in cells after epigenetic unmasking, and subsequent validation identified sphingomyelin phosphodiesterase 3 (SMPD3) and neurofilament heavy polypeptide (NEFH) as tumor suppressor genes differentially methylated in HCC [ 25].
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Studies of T cell responses during immunotherapy have largely used approaches based on analysis of overall populations of cells or on cytokine-producing sub-populations of cells derived after antigenic stimulation.
Examples of computational approaches to drug repurposing include side effect-based approaches, in which similarity between drug effects is used to suggest drug targets and drug indications (Campillos et al., 2008), data mining of clinical records (Tatonetti et al., 2012) and approaches based on analysis of GWAS data (Sanseau et al., 2012).
In this paper, we propose a hazard analysis approach based on Architecture Analysis and Design Language (AADL).
This paper presents a recurrence plot-based traffic classification approach based on the analysis of non-stationary "hidden" transition patterns of IP traffic flows.
Pinch analysis, which is an approach based on thermodynamic analysis and composite curves, is the most widely used in the industry.
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