Extensive in vitro testing coupled with promising early clinical data has provided an enhanced appreciation of ImmTAC function in vivo and indicates their potential therapeutic benefit in terms of a durable response and ultimately the breaking of T cell tolerance.
Furthermore, a detailed appreciation of the function of these EBV latent genes could provide opportunities to develop novel diagnostic and therapeutic approaches.
However, with the wider appreciation of the function of programmed cell death in cardiac diseases, this view is undergoing considerable change.
These suggest that better appreciation of placental function in utero may provide an opportunity to identify pregnancies at risk of stillbirth to target intervention [ 22, 23].
As we begin to appreciate the potential complexity of these molecular networks, there is increasing interest in modelling pathways in order to expand our understanding of biology from the traditional gene-centric view of life, to a systems level appreciation of biological function.
This is not necessarily always the case and alternative insights were recently revealed by the use of new high throughput techniques, which allow the agnostic mapping of such regions and an unbiased appreciation of their functions.
This chapter provides an introduction to systems wherein interactions among the components take place, including an appreciation of the functions and mechanisms.
Just to make sure it's all good, you're purely focused on the sensation and the appreciation of the functioning and feeling of your perfectly designed earthly body.
The assessment of collective appreciation of the functions of forests and other landscape components is useful for opening discussions about landscape management strategies.
Despite growing appreciation of the functions and regulatory processes in which sRNAs participate, little is known of how sRNAs evolve within bacterial lineages (Waters and Storz 2009; Gottesman and Storz 2010).
Appreciation of the role and function of enabling factors and themes identified in this study, as well as their interrelationships, is likely to increase the likelihood of accreditation programs being implemented effectively.
