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A fundamental role for inflammation in atherosclerosis and its complications has become appreciated recently.
These consequences are only becoming appreciated recently, after the use of lead additives in fuels has decreased.
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The magnitude of this problem was not fully appreciated until recently, when research established the significant burden of surgical conditions.
Over the last ten years the diversity of G-proteins and importance of the individual constituent subunits have been appreciated, and recently the specific molecular mechanisms, through crystallisation advances, have been elucidated.
However, Shelley's biographies have not been fully appreciated until recently.
The fundamental biology of oxidative damage and the physiology of antioxidant defense have been at the focus of a large body of biomedical literature (e.g. [3]), but the role of prevention or repair of oxidative damage in shaping the evolutionary ecology and behavior of organisms in the wild has been fully appreciated only recently (see [8] [11]).
The contribution of Notch to vascular biology has been appreciated only recently.
Further, the contributions of SIRT1 functions in different tissues in maintaining organismal physiology are being appreciated only recently [ 36, 37].
The contribution of CNVs in the psychiatric disorders has been appreciated only recently with the implementation of array technologies that enable genome-wide determination of CNVs.
8 ST2 is a stable cell surface marker on T(H 2 cells, yet it has become appreciated more recently that ST2 is functionally expressed on epithelial cells as well.
What has been less widely appreciated until recently is that a subset of obese individuals remains free of any of these metabolic abnormalities.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com