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There was appreciably reduced expression of mature (glycosylated) DAT for mutants Ala314Val, Arg85Leu, and co-expressed Arg445Cys Arg85Leu.
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Consistent with the observations in Hdac1ATG1 morphant embryos, the expression pattern of ascl1b was also appreciably reduced in individually genotyped hdac1 mutant embryos at 12 hpf and 18 hpf, in comparison to its expression level in wild-type sibling embryos.
In making drugs illegal, we haven't appreciably reduced use.
The emission levels of hydrocarbon and NOx are appreciably reduced with the addition of CON.
Additionally, the impoundments have appreciably reduced the tidal prism by at least 50%.
During World War I, Widal prepared an antityphoid paratyphoid vaccine that appreciably reduced typhoid contagion among the allied armies.
But the minimum wage has never reached the floor set for a "living income" and has not, therefore, appreciably reduced the bill for wage subsidies.
Although insurgent attacks have been appreciably reduced and Al Qaeda in Iraq is devastated, considerable distrust remains among various ethnic factions and religious sects and within the Iraqi government.
Yet, overall, they have not appreciably reduced the prevalence of persons with serious mental illnesses involved in the criminal justice system.
It was observed that the plastic and deformed zones surrounding the excavation area got appreciably reduced after the recommended support installation.
Experimental results revealed that doping with Li+, B3+ and Bi3+ resulted in appreciably reduced grain size and increased density leading to enhanced optical transmittance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com