The phrase "appreciably change when" is correct and usable in written English.
It can be used to describe a significant or noticeable alteration that occurs at a specific time or under certain conditions.
Example: "The results of the experiment did not appreciably change when the temperature was increased."
Alternatives: "significantly alter when" or "noticeably shift when".
According to qRT-PCR analysis, HIF-1α mRNA levels did not appreciably change when DNMT1 or DNMT3b were knocked down as compared to control cells (Fig. S3C&D).
Reverse causation is improbable, because the trend estimates did not appreciably change when the first 3 years of follow-up were excluded (although some trends became non-significant, presumably due to smaller numbers of cases).
In the subset of men with information on HBV and HCV, associations did not appreciably change when we adjusted for HBV and HCV, or when the analysis were restricted to those lacking HBsAg (men diagnosed with liver cancer: 98.7% men who died from chronic liver disease: 99.6% controls: 99.2%), or HCV (93.7%, 96.8%, 99.6%, of cases and controls, respectively; Supplementary Table 1).
In our study, the positive association between di- ortho PCBs exposure and birth weight was not appreciably changed when fish consumption during pregnancy was added to the regression model, thus indicating that omega-3 fatty acids in fish are not responsible for the observed association for di- ortho PCB.
The subsequent decoding did not appreciably change quality when performing the GPFA step on the T-maze and S-maze separately.
It applied also to the T2, T3 and T4 mutants, but gM-T1, while again perinuclear without gN, did not appreciably change its distribution when gN was co-transfected (Fig. 4B).
This adjustment did not appreciably change the associations; however, when intakes of snack-type foods were added to the unstratified models, which included a BMI×snacking frequency interaction term, all associations were attenuated to null (results not shown).
To our knowledge, the ScAGU115 is the first enzyme that does not appreciably change the cell wall in planta while exhibiting normal activity when extracted.
Missing values were coded as a separate category for each variable; when excluding subjects with missing values the results did not appreciably change.
When hydrogens are substituted with a dimethyl, the relative reaction rate (krel) may not appreciably change, although the result depends on the system and the position of the substitution [14].
When the first 3 years of follow-up were excluded, the trend estimates did not appreciably change (see Table 5).
