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It is unclear at this point, based upon published literature, whether radezolid has any appreciable safety advantages over linezolid.
The fact that the study has been completed suggests that there have been no appreciable safety concerns and that there are indications of efficacy.
The discovery and development of MRP1 inhibitors with high efficacy and appreciable safety have been much more difficult than those of P-gp, mostly because MRP1 is an anionic transporter.
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National surveys reveal weak correlations between actual and perceived increases in violence at the state level, which may lead people to think that moving domestically will not lead to an appreciable increase in safety.
A 2010 study showed that nearly half of the guns that crossed state lines before being recovered in crimes came from just ten states, most with comparatively weak gun laws, indicating that weak gun laws in other states have already had an appreciable negative public safety impact on states like New York.
Efficient geometric design and signal timing not only improve operational performance at signalized intersections by expanding capacity and reducing traffic delays, but also result in an appreciable reduction in traffic conflicts, and thus better road safety.
The symptomatic care was the major reason for professional eyecare visit and appreciable proportion of the respondents does not regularly indulge in eye safety practices.
Also, no appreciable net change was observed among pediatricians who reported that parental concern with vaccine safety would be a barrier to rotavirus vaccination (26% reported vaccine safety to be an increased barrier, whereas 23% reported it to be a diminished barrier; P = 0.75).
Compounds showing appreciable spermicidal activity at ⩽0.5% [3c, 4d (0.5%); 2c, 3d (0.1%); 2d, 4c (0.05%)] were tested for safety studies against human cervical (HeLa) cell line.
Although infection control and safety measures have improved steadily since the discovery of the epidemic, the totality of the evidence suggests also that appreciable HCV transmission is likely ongoing up to the present.
They have no appreciable gravity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com