"appreciable effect in" is a correct and usable phrase in written English.
You can use it when describing a noticeable result that has happened as a result of something else. For example, "The teacher's dedication and enthusiasm had an appreciable effect in improving the students' reading comprehension."
In fact, MHC class I allele effects may be strongest in modifying organ-specific diseases induced by HIV independent of any appreciable effects in the periphery.
Because ultrasound stimulation alone at an acoustic pressure of 570 kPa caused no appreciable effect either in in vitro or in vivo experiments that were carried out in our laboratory, it is unlikely that the observed effects in the combined treatments could result if bubbles were excluded.
It has been previously reported that overexpression of IL-8 in ovarian cancer cells had no appreciable effect on paclitaxel resistance in vitro (Duan et al, 2002).
FRS2 and FRS3 suppression in contrast, did not have any appreciable effect on EGF stimulation in either of our prostate cancer cell models.
Of note, ML-60218 was used at a relatively non-toxic concentration, such that it did not produce any gross abnormality in the zebrafish larvae, and it had no appreciable effect on tRNA levels in the pancreatic cancer cells.
The block of cap-dependent translation by rapamycin, a mTOR inhibitor, had no appreciable effect on VSV growth in NIH 3T3 cells, but drastically reduced viral yield in activated T-lymphocytes [10].
It was shown that while hydrogen dilution alone does not have an appreciable effect on cell polarization, in the presence of trace amounts of CO, hydrogen dilution amplifies the problem of CO poisoning.
We found that ezrin-T567D had no appreciable effect on cell spreading in response to EPAC1 and PKA activation with F/R (Fig. 6).
