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However, because neither J.Vav cells nor Vav1−/− T lymphocytes show appreciable defects in TCR-induced actin polymerization (Fig. S1 and data not shown), we reasoned that the requirement for GEF activity must be conclusively addressed in T cells in the VavNULL background.
Although Gas1-LacZ expression in the GI system is detected early, we did not find appreciable defects in the gut tube at E10.5 and E11.5.
Thus, none of the single iron transport system mutants of Shigella displayed appreciable defects in intracellular multiplication or cell-to-cell spread, although a mutant deficient in three distinct iron uptake systems failed to replicate within epithelial cells.
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If the het mice lack any appreciable defect in free running circadian period, activity consolidation, phase angle of entrainment, such lack of phenotype may be explained in the discussion section.
From these figures, we can see that the intensity ratios of D/G are not increased by stretching, indicating that stretching does not introduce appreciable defects.
Previously we demonstrated that a mutant A/WSN/33 (H1N1) influenza virus with defective M2 ion channel activity did not show appreciable growth defects in cell culture, although its growth was attenuated in mice (T. Watanabe, S. Watanabe, H. Ito, H. Kida, and Y. Kawaoka, 2001, J. Virol. 75, 5656 5662).
"Zero defects in America," Rapaille said.
"There were defects in the brain.
Defects in a single gene.
Evaluate any defects in the lawsuit.
These factors were more appreciable in children in HEA.
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