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FLG and FLG-COOH accumulated within organs induced significant cellular and structural damages to lungs, liver, spleen, and kidney, ranging from mild congestion to necrosis, fibrosis and glomerular filtration dysfunction, without appreciable clearance.
Overexpressing miR-122 infectedted liver tissue showed appreciable clearance of hepatic parasite burden with a recovery of serum cholesterol.
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An appreciable difference is observed at high overtolerances where the 3-D model predicts cut-off clearances (clearance at which the interfacial pressure starts to drastically drop) which are about 30% lower than those predicted by the axisymmetric models.
Inclusion of body weight as a covariate for levodopa clearance did not improve the model fit to any appreciable extent.
Inclusion of body weight as a covariate on levodopa clearance did not improve the model fit to any appreciable extent (3.5 and 5.9 points reduction in nonmem objective function for fixed 0.75 or estimated allometric exponent for relationship between levodopa clearance and body weight, respectively, P > 0.01).
Besides the bone, an appreciable amount of activity was found in the kidneys, which is reasonable according to the compound's renal clearance.
Reducing tip clearance both improves performance and reduces noise, not only at the maximum efficiency operating point but also in an appreciable low flow rate operating region.
They have no appreciable gravity.
And it's all appreciable.
That is obviously not an appreciable decline.
Otherwise, appreciable migration would be highly unlikely".
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CEO of Professional Science Editing for Scientists @ prosciediting.com