Sentence examples for appreciable binding from inspiring English sources

Ponezumab was also reported to bind monomeric, oligomeric, and fibrillar forms of Aβ 1-40) but did not show appreciable binding to monomeric, oligomeric, or fibrillar forms of Aβ 1-42) [ 207].

This indicates that for the activation process, no appreciable binding energy is required.

The TPUII also exhibits an appreciable binding affinity (kD = 7.52 μM) for CAIX.

On the basis of receptor-binding displacement assays in rat brain and glioma cells, 9 had appreciable binding affinity and displaced a prototypical PBR ligand, Ro 5-4864, wIC50IC50 values between 289 and 390 nM.

The selected compounds showed appreciable binding to the binding site of MMP-2 and MMP-9 proteins as determined by analyzing their bonding interactions in terms of H-bond, hydrophobic interactions and binding free energy (− ΔG, kcal/mol) of the selected best docked poses (Table 2).

Binding of carcinoma cells to E-selectin was specific as evidenced by the lack of appreciable binding in the presence of a function blocking anti-E-selectin mAb.

Due to its poor water solubility, dimer 13 did not give any appreciable DNA binding or cytotoxicity.

It is apparent from the nonspecific autocorrelation data that there is no appreciable nonspecific binding as there is no correlation seen, meaning the correlated events giving rise to G in Figure 1A C all arise from the specific binding interactions between CTB and 1 mol % GM1.

Hotspots are the interface residues that contribute maximally toward the stability of the complex, and when mutated to alanine, they impart an appreciable decrease in binding strength (difference of 2 kcal/mol or more in the binding energy).

We found that reversion of three residues introduced by somatic hypermutation (SHM) in the variable heavy chain domain to germline (light chain, LC; heavy chain, HC) (LCWT HCIGL; CDR H3 is retained fully mature) had no appreciable impact on binding of full-length or cleaved EBOV, BDBV or SUDV GP or neutralization of rVSVs bearing EBOV, BDBV or SUDV GP (Fig. 5b,c and Supplementary Fig. 6).

Most cognitively healthy normal controls (NC) do not show appreciable amyloid tracer binding.