The phrase "appreciable adverse effects" is correct and usable in written English.
It can be used in contexts discussing the noticeable negative impacts of a particular action, treatment, or policy.
Example: "The new regulations may lead to appreciable adverse effects on small businesses, impacting their ability to operate effectively."
Alternatives: "significant negative impacts" or "noticeable harmful effects".
These treatments had no appreciable adverse effects on the mice.
No appreciable adverse effects were observed with this treatment, suggesting that CN-A may be useful in treating leukaemia and other malignancies.
The effective Uncl-Sema3E concentrations achieved in the blood of mice subject to systemic delivery are in the low-micromolar range, similar to those applied for the validated VEGF-trap sFlk1, and they did not induce appreciable adverse effects.
"Recent financial market developments were thought unlikely to have an appreciable adverse effect on capital spending," Fed officials concluded.
In addition to consideration of carcinogenicity chemical structural alerts, genotoxicity, and other required information, the TOR is deemed by the agency to be the level below which a contaminant in food would not be expected to have an appreciable adverse effect.
When given intravenously on a weekly basis, in some cases for more than 3 years, onconase was remarkably well tolerated in the vast majority of patients, with no appreciable adverse side effects attributed to immunogenicity of the reagent.
Recently developed novel uroselective antagonists had demonstrated appreciable cardiovascular adverse effects.
Doses of OTA, or exposure limits, determined to be without appreciable risk of adverse effects, have been derived by regulatory agencies and authoritative bodies.
This is why a patient suffering from cancer may be justifiably treated with radiation therapy, although the adverse effects may be appreciable.
As in the case of calibration curve construction, appropriate criteria should be applied; again, we note that exclusion of observations on the basis of low probability of occurrence (e.g. 1% or below) is unlikely to lead to appreciable bias but will avoid the adverse effects of amplification failure on higher-concentration samples.
Treatment burden and adverse effects can have an appreciable negative impact on patients' quality of life (QOL) with prior studies showing that interventions with a high treatment burden for treating glucose (glycemic disutility) may substantially attenuate benefit as measured by quality-adjusted life-years.
