Sentence examples for appraisal and refinement from inspiring English sources

Translating preclinical findings into new treatments for human osteoarthritis requires a critical appraisal and refinement of animal models, identification of those pathogenic mechanisms that are amenable to intervention, and pharmacological targeting of those mechanisms in the right people at the right time.

As the use of human hepatocytes from liver donors has eclipsed the rat equivalent, both steps of the mechanistic extrapolation approach have received re-appraisal and suggested refinement in recent years.

The team engaged in all aspects of this study including the identification, appraisal and synthesis of the literature, and development and refinement of the evidence-informed recommendations.

And "Still Lives" needs editing and refinement.

Its lavish appointments suggest breeding and refinement.

Others showed more finesse and refinement.

Farruco has much more elegance and refinement.

And refinement is passé, and seems pretentious or phony.

Tastefulness and refinement have never been its calling cards.

Instead, audiences encountered a performer of skill and refinement.

It's born of constant experiment, reassessment and refinement.