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To analyze the effects of time, medium and concentration on the expression of ER and PR as well as proliferative activity, a linear mixed model was performed appointing time and media as repeated measures.
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The appointed time came and went.
Even then, it didn't happen at the appointed time.
At 9 A.M., the appointed time, they were nowhere to be found.
The capsule entered the atmosphere at the appointed time, with thrusters guiding it toward the crater.
We had several calls scheduled, but Chuene never picked up his phone at the appointed time.
"And what do I find at 2 25 p.m., the appointed time?
"Any guest who stays up past the appointed time should go to the Lunar Lounge".
As the members of the group arrived at the appointed time, the giddiness increased.
We are, in a way, freaks living well beyond our appointed time.
"Like melancholy moods...they steal into the gloom of that appointed time".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com