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Having found that the McSad, in addition to being valid, also appeared to perform better than the EQ-5D classification system in reflecting the range of depression states, we can recommend applying this instrument in valuations of depression that can subsequently be used in cost-utility analyses of psychological interventions for patients with somatic conditions.
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Science educators can apply this instrument to teacher behaviors and use the data to improve classroom inquiry instructional methodology.
We have now applied this instrument to image the distribution of DNA-bound Ca2+ and Mg2+ in dinoflagellate chromosomes, a goal that could not be attained earlier by analytical electron microscopy.
We applied this instrument in a population survey in NZ in order to describe the range of experiences of men and women with aggression in intimate partnerships, and the involvement of alcohol at the time of aggressive incidents.
Still, making such a psychometric study in a multicenter setting was beyond our logistic capacities, and it would be of interest to apply this instrument in other French-speaking regions.
As an exemplar application, we have applied this instrument to study the aggregation of HIV-1 Gag proteins in VLP formation at the cell membrane, which is challenging because the unknown stoichiometry of the fluorescent protein expression can mean that the average change in the donor fluorescence lifetime over the field of view is rather low, that is, a few hundred picoseconds.
We applied this OCT instrument to a model of Tropomyosin-associated DCM established in adult Drosophila.
A concern that arises when applying this method is that of instrument strength.
Our data largely support the theoretical structure and stringent demands of the CVF model as applied to this instrument.
Two further modifications were applied to this instrument: a wide-end flight tube to allow simultaneous measurement of ions with large mass differences, such as U Pb or Li Li, and the addition of an electrostatic energy filter before the Daly detector to enhance abundance sensitivity measurements.
The information required for applying the instrument is difficult to obtain and often not readily accessible.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com