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By applying stringent criteria, we could detect known and novel pathogenic variants with no false positives.
By applying stringent criteria for support of the gene model, the authors excluded 649 of the original 741 sequences as unlikely to be real genes.
Applying stringent criteria, we identified significant differential methylation among the tumor subtypes in 15 of the 1,505 screened CpG islands.
This might be due to the fact that we also used Illumina and by combination with FLX sequencing as well as applying stringent criteria for annotation thus resulted in the least number of nTARs.
By applying stringent criteria (distinct folds) Omelchenko et al. concluded that at least 1/10 of all enzymes with presently assigned complete EC numbers could have emerged in evolution more than once.
By applying stringent criteria for the determination of coding and non-coding nTARs (nc nTARs), we assigned 26 and 70 novel bona fide open reading frames (ORFs) for C. albicans and C. dubliniensis, respectively (Additional file 6).
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Most vetting is at the author application and invitation stage, when we apply stringent criteria to find suitable authors.
We applied stringent criteria for alignments.
In this context, we applied stringent criteria to define a list of high confidence direct targets.
In particular, we applied stringent criteria to detect complications related to metallic stent placement, removal and their sequaelae.
It is also possible that the applied stringent criteria might have missed the prediction of potential target genes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com