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Single-cell gene expression profiling is feasible using qPCR, applying carefully optimized targeted preamplification.
Noticeable, the majority of the false positives were detected at higher Ct values than the true positives indicating that applying carefully chosen Ct detection thresholds is a reasonable approach to ensure acceptable false discovery rates.
Applying carefully calibrated molecular clocks on broad extant taxon sets and reconstructing characters on dated ancient lineages are indispensable for interpretation of enigmatic key fossils such as Halkieria or Nectocaris that may form part of the early evolutionary history of the group (e.g., [ 24– 24]).
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Some cancer drugs are extremely potent and will harm healthy cells if not applied carefully.
Governor Quinn said last fall that he supported the moratorium as well as capital punishment "applied carefully and fairly".
AIDS advocates have generally expressed optimism that the strategy, if applied carefully, could help reduce the approximately 50,000 new H.I.V. infections that occur annually in the United States.
Dithranol, a paste still used today, had to be applied carefully to ensure it was only on the plaques, not on healthy skin where it would burn.
They sensed the onset of the firing with one set of electrical probes and applied carefully tailored electric fields with another, shutting the firing off and returning it to something like normal behavior.
If necessary, apply insecticides to areas of insect activity – Residual insecticides, available in aerosol cans, can be applied carefully to suspected areas of infestation like cracks and crevices, along baseboards, etc. Insecticide dusts are effective when applied into wall voids.
Like all industrial policy arguments, this has to be applied carefully; something that could be a good idea in principle might be a very bad idea once you do the numbers, and these numbers are hard to do.
However, he certainly found this notion useful as long as it is applied carefully.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com