Although both factors are regarded as predictive for the PFS outcome, the between-study differences are small, hence performing an indirect treatment comparison (ITC), without applying adjustments for patient characteristics variations, was regarded as an appropriate approach.
These estimates rely on available data in national household surveys, especially the Demographic and Health Survey (DHS) and UNICEF's Multiple Indicator Cluster Survey, applying adjustments for maternal reporting of the child's size and for heaping of birth weights on multiples of 500 grams [ 23].
We applied adjustment for age and education when appropriate and used pathological cut-off values as established elsewhere [27] [33].
Since model 2 turned out to be more accurate compared to model 1 with regard to c-statistics, goodness of fit and explanatory power, the authors would prefer to apply adjustment for frequency of readmission.
After applying adjustment scenarios to account for potential overlap between data sources, we estimated over 92,000 individual opioid users.
Two of the polls, from Grove Research and the Mellman Group, generally show strong results for Democrats, which give them less impact in the forecast after applying our adjustment for pollster "house effects".
Given the high correlation between the pathologic and cognitive traits, applying an adjustment for 68 tests would be overly conservative.
Despite the fact that the high number of tested hypotheses might need a Bonferroni correction on this threshold, being the hypothesis of this study verified if P value was higher than the threshold of significance, we adopted a conservative approach without applying any adjustment for multiple comparisons.
But one innovation that we might consider in future years is to also apply an adjustment for the variance or "swinginess" in a poll.
Unable to accurately reflect short-term glycemic variability, HbA1c has delayed effects when applied in adjustment for glucose-lowering treatments.
