Exact(1)
By applying a depletion strategy for NK (and NK-T) cells with an anti NK1.1 antibody, it was shown that NK cell removal protected mice from acetaminophen hepatotoxicity, as assessed by reduced serum transaminase and necrotic area compared to isotype antibody treated mice (Liu et al. 2004).
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To address this question, we applied a dopamine depletion protocol easily and reliably usable on young rats (see methods).
Oxidizing the GaAs cap layer locally by applying a voltage to the AFM tip leads to depletion of the electron gas underneath the oxide.
In addition, the capacitance-volt (C-V) measurement was also used to examine the mechanism of photovoltaic performance enhancement due to the depletion width being enlarged by applying a DC voltage on an ITO-electrode.
In the present study, we investigated RA patients in whom an extended period of B-cell depletion during a 2-year period was achieved by applying a fixed retreatment protocol with rituximab, an anti-CD20 B-cell-depleting mAb [ 8].
We have implemented a simple GSE method applying a hypergeometric statistical model and Fisher's exact test to detect GO term enrichment, depletion, or both [ 45].
Applying an appropriate bias to the devices can induce depletion of the channel of free carriers, leaving behind immobile charges, i.e., ionized dopants.
To determine whether p97 completely traverses the BBB or still resides within the circulation (mainly capillaries), the compartmental distribution of 125I-p97 after i.v. injection was analyzed by applying the capillary depletion method to the cerebral cortex.
Therefore the present study, applying lifelong Nox4 depletion in HUVECs in the absence of any pharmacological treatment, demonstrates for the first time that replicative senescence of human endothelial cells can be delayed by reducing endogenous Nox4 activity.
An alternative way to signal the flux of substrate through the OB pathway was to use a direct approach whereby a sclerostin effect was applied to the depletion rate of ROB and a separate effect was applied directly to the OB accumulation rate.
The applied DNase depletion protocols recommended for each of the tested method should in theory have removed moderate amounts of DNA (<50 μg DNA/ ml RNA extract).
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