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Many of the issues pertinent to the quantification of labeled peptides also apply when analyzing label-free data; however, there exist additional challenges related to comparing peptide abundances across different LC MS data files.
Although the scientific relevance of statistical interaction is pertinent, the main disadvantage of the case-control design susceptibility to bias when estimating effects of exposures that are measured retrospectively does not necessarily apply when studying statistical interaction between genotype and environmental exposure.
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Only when "pertinent," its stylebook says.
Chaperones as clinically useful biomarkers are mentioned when pertinent.
Proportions were compared between groups using ×2 tests, and when pertinent, the two-sided Fisher test.
Labels are ignored in meta-regression analyses (though displayed in plots when pertinent).
Additionally, sex, age, joint (hip/knee), surgical findings, and isolated organism were recorded when pertinent.
When pertinent, we stratified countries into income groups based on contemporaneous World Bank income-group classifications.
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