Researchers who wish to access the information must apply to de-anonymise the records of those patients who have opted-in to the register.
However, to be protected the information must be 'individually identifiable.' HIPAA does not generally protect data held in publicly available repositories because the Privacy rule generally does not apply to de-identified health information [ 23].
Fab antibody display on filamentous phage is widely applied to de novo antibody discovery and engineering.
Resultant paired-end reads were applied to de novo assembly using SOAPdenovo2 version 2.40 (Luo et al. 2012) with different k-mer from 21 to 81.
The work flow which comprised 3D-QSAR modeling, Topomer Search, MFR, molecular docking and evaluating criteria could be applied to de novo drug design and the resulted compounds initiate us to further optimize and design new potential ALK inhibitors.
NGS technology was successfully applied to de novo and re-sequencing of entire prokaryotic genomes [ 9] and to re-sequencing higher eukaryotes including humans [ 10- 13].
Currently, the PacBio platform is widely applied to de novo sequencing for various organisms, including human [ 36, 37], microorganisms [ 38, 39] and plants [ 40].
In the past years, PacBio sequencing has been applied to de novo assemble or resequence a variety of genomes (from small microbe to human), characterize the complexity of transcriptomes at the isoform level, and study base modifications.
The radio signal (which resembles noise) is plucked from the air by the receiver, and the appropriate pseudo-random code is then applied to de-spread a chunk of the signal.
In addition to the traditional application of a client verifying the storage content at a remote server, PGV can also be applied to de-duplication scenarios where the server wants to verify whether the client possesses a significant amount of information about a file (and not just a partial knowledge/fingerprint of the file) before granting access to an existing file.
