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The aspirational businesses that will truly define the 21st century--what Klaus Schwab at the World Economic Forum in Davos this year called the 4th Industrial Revolution--will be organizations that apply ingenuity to solve the big problems facing our planet.
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He is something of a narrative engineer, the kind of literary inventor who applies ingenuity to problem-solving, as opposed to one who sets off on a path to see what he can discover.
The show argues that design is not solely the preserve of professional designers but can also be the work of scientists, activists, computer programmers, hackers and anyone else who applies ingenuity, originality, strategic thinking and other qualities that are indispensable to good design.
Yet three days later, after applying ingenuity, courage, and an incredible amount of fortitude to solving the many "unsolvable" problems, the astronauts were standing on the deck of an aircraft carrier.
To identify interaction networks enriched in stem cells, we applied Ingenuity Pathway Analysis for the components containing stemness-on modules (components B and C, Figure 4).
Networks were generated by applying Ingenuity pathways analysis (Ingenuity Systems, Redwood City, CA, USA).
To identify enriched signaling pathways among differentially expressed genes, we applied Ingenuity pathway analysis (IPA Ingenuity Systemsms, Redwood City, CA, USA, [ 13]) and DAVID functional analysis [ 14].
To study the transcriptional changes induced by TMPRSS2-ERG gene fusion, we applied Ingenuity Pathway Analysis software to investigate overrepresented pathways among the genes with significant upregulation in fusion-positive tumors.
We also applied Ingenuity Pathway Analysis (IPA) software (Ingenuity Systems, Inc., Redwood City, CA), a structured network knowledge-based approach, to evaluate functions and to elect putative interaction and signaling mechanisms through which IL-10 plays a role in pulmonary pathogenesis in response to O3.
Why not apply the ingenuity that currently goes into massaging the planning system, such that multi-level basements might be permitted beneath historic houses, to addressing the city's larger needs.
Here in the U.S. we have learned how to apply human ingenuity to the problem of building our economy while polluting less.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com