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Mathematical treatments are usually applied for the correction of this variability, being the most common derivation, standard normal variate (SNV) and multiplicative scatter correction (MSC).
Therefore, our novel artificial standard probe may be effectively applied for the correction of chip-to-chip variations and quantitative data analysis of a one-color labeled DNA microarray system.
The surface temperature history applied for the correction is shown in Fig. 2.
Further, they are used to obtain a regular series of baseline values applied for the correction of 1-min (or 1-s) data, which are derived from continuous variometer recordings.
Bonferroni correction was applied for the correction of multiple testing.
Alternatively, the less conservative Holm correction was applied for the correction of the data [ 24].
The Bonferroni procedure was applied for the correction of multiple testing.
In order to shorten the examination period even more, alternatives are to shorten the transmission (or a CT-based) scan [6] which is applied for the attenuation correction or to eliminate the transmission scan.
The method of Benjamini and Hochberg was applied for the multiple corrections with a p-value cut-off of 0.05 and fold change ≥±2.0 to obtain the statistically significant genes.
We performed unpaired t-test with a p-value less than 0.05 and Benjamini Hochberg false discovery rate (FDR) was applied for the multiple corrections to filter the false positives so that the statistically significant genes could be obtained.
In addition, to predict the GM concentration, the same statistical model for the interaction of age by groups was applied with the correction for IQ and the global mean voxel value.
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