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Exact(10)
The use of a model that eliminates the need to apply correction factors to repolarization indices helps to clarify the role of the autonomic nervous system on ventricular repolarization.
In the available beam theories, we have to apply correction in case of deep beams.
For some compounds, it may be necessary to apply correction factors to arrive at more accurate predicted logP values.
However, for the present integrated approach it may be sufficient to use the more readily available equilibrium dialysis brain homogenate binding assay and apply correction factors on the basis of drug pKa[12].
Libatique explained, "Basically, it unifies all the color...When you try to apply correction, the film moves in very strange ways".
We did not apply correction for multiple testing in this exploratory screen because of the availability of the highly similar PIVUS cohort for replication.
Similar(50)
It was not until the introduction of computers in the 1960s that it became possible to apply corrections more accurately and more rapidly.
The calibration made it possible to estimate errors and to apply corrections to reduce the uncertainty of measurements.
In this method we need not apply corrections.
This yields great flexibility, allowing us to apply corrections based on known constraints or data available.
As a result batch effects and experimental effects might be confounded and usually applied correction methods such as ComBat and SVA are not effective48, 49.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com