Exact(1)
Keeping in mind that from a clinical point of view tissue- and in detail ISF-concentrations are often considered better evidence of drug effectiveness than serum concentrations [ 13, 14] it is the therapeutic aim to apply a dosing scheme that will result in a drug concentration in the ISF above the minimal inhibitory concentration (MIC) [ 15].
Similar(59)
It helps a great deal to apply a dose or two of liquid fertilizer to be sure the bulb receives the proper nourishment.
Who better to apply a dose of fatalism -- you got no choice, kid -- than someone who began cutting hair for a living in Sicily when he was 12 years old?
So if they're aggressively buying while the little guy is panicking, who do you want to follow?" Following the "house" has always been our strategy at the Buyback Letter, but we apply a dose of caution when evaluating companies that are buying back their own stocks.
Bissell's orders specified Vincent take the position of Chennault's executive officer, to apply a dose of West Point regimen to the haphazard CATF paperwork, but Chennault, irked at this maneuver by his 2200 mile distant superior, instead assigned Vincent operations officer.
Participants were instructed to apply a dose once daily, preferably at bedtime.
Then Krzanich stepped in, and applied a dose of reality: Intel continues to look at the business model … we are not experts in the content industry and we're being careful".
"This is a program that makes a silk purse out of a sow's ear," Ms. Berger asserts, tongue in cheek, in regard to the three projects — "Best Pedestrian Route" on John Street, "Fulton Fence," and "Concrete Jungle" on Broadway between Ann and John Streets — that have successfully applied a dose of colorful camouflage to concrete barricades and other eyesores.
We applied a dose of 2 mg/kg, whereas a typical dose used in clinical practice is 5 mg bid via an oral route.
When RIR is applied, a dose-response relationship is established for shape A in 5% of the simulated samples.
Participants applied a dose of 40 drops of study solution (about 1.3 mL) to the affected knee 4 times daily for up to 6 weeks.
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