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Whereas the baseline algorithm applies the edge-linking uniformly to all edge pixels to segment a region, the modified algorithm selects high potential edge areas in the region by analyzing the surface fit pattern and gives priority of edge-linking to those areas.

After binarization, we apply the edge tracking algorithm [ 25] for fast object labeling.

One remedy to suppress such noises is to apply some smoothing filter in advance of applying the edge detection filter.

Manual exfoliation of the cells was accomplished by applying the edge of a glass slide to the exposed surface of the opened colonic resection specimen and gently scraping it.

For this purpose, an exponential cost function is used that incorporates the edge information obtained after applying the edge-enhancement algorithm formerly designed for the fingerprint enhancement.

To sharpen the velocity edges for the traveltime tomographic results and fit data at the same time, we should apply the edge-preserving concepts to regularize the inversion.

An over-segmented object was wrongly split into two or more smaller objects due to high intensity values in inner-object regions when applying the edge-detection filter (see section on Automated Image Analysis).

Effects of applying the edge-preserving bilateral filter to data simulated at higher noise levels showed similar improvements as were observed for data simulated at normal noise levels (Table  1 and Supplementary Fig.  3b).

Figure 4 shows a sample image, detected edge points after applying the Canny edge detector, and edge point groups after applying K-means clustering.

Applying the Canny edge detection algorithm with a smoothing Gaussian of width 2.0 Å accurately identified the edges between the two phases (Fig. 3a).

Fig. 6 Result of applying the Canny edge detector algorithm to Fig. 5.

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