Although the approach in Goldzsmidt et al. (1993) also applies the Specificity Principle, it does so in a different way, namely by minimizing the weigthed sum of violations where weights are attributed to violations in view of specificity considerations.
The same applies to specificity; in this case the sample consists of nondiseased controls.
In order to maximize the predictive value of these matches, ETA next applies distinctive specificity filters evolutionary similarity, function plurality and match reciprocity.
We then applied this specificity toward the "methylation state" and combined it with specificity toward lysine position in the design and synthesis of a peptidic probe targeting H3K36me2 JHDMs.
The kind of fiction I like to read and write is very specific and detailed about everything — settings, moods, smells, textures — so to me it's kind of silly or coy not to apply that specificity and detail to sex, and I don't see the point of coy fiction.
Because the foundational methods developed here are structure based, these results suggest that the approach can be more generally applied to specificity prediction and redesign of other protein protein interfaces that have structural information but lack phage display data.
The corresponding isotype control antibody (R&D Systems) was applied for specificity control.
Depending on the PSA cutoff values applied, the specificity and sensitivity of PSA range from 20 to 40% and 70 to 90%, respectively [ 40].
On multivariate analysis, however, the majority of patients from both groups were correctly classified irrespective of the classification program applied (SPSS/CLASSIF1; specificity: 80.4%/97.8%; sensitivity: 86.2%/72.4%; and negative: 90.2%/84.9%; and positive: 73.5%/91.3% predictive values) (Table 3).
The same case-by-case specificity applies to economies and structural reforms.
