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The displacements applied were calculated trigonometrically using SolidWorks.
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The pressure applied was calculated to be 25 MPa.
The sum of the differences in weight of material applied was calculated for each participant.
The predicted thermal dose volume (PTV) applied was calculated by the MR-HIFU system and defined as the volume receiving a thermal dose of 240 equivalent minutes at 43°C (threshold value for thermal ablation) [ 18].
The actual applied concentrations were calculated based on the mean measured concentration directly before and after application.
From the external forces, the geometry of the foot, and the strain measurements, the applied torques were calculated.
However, RRs and applied CIs were calculated for our outcomes of interest to compare and interpret outcome data.
For each subject, the applied torque was calculated as the applied force multiplied by the lever arm.
All tests were applied two-tailed and were calculated using the software package SPSS (version 16.0).
Mean colour changes applied to each face were calculated (by face dataset).
Dose ratios were applied and combination indices were calculated (Table 1).
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