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Previously, IKK targeting strategy has been successfully applied to sensitize neuroblastoma [ 37] and prostate cancer cells [ 38] to TRAIL.
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Specifically, motion probing gradients are applied to non-directionally sensitize water molecules in order to determine water movement between diffusion-sensitizing gradient pulses [ 9].
The clonogenic assay was also applied to determine whether HIF-1α-siRNA or CTM sensitized glioma cells U251MG and U343MG to radiation.
In brief, 100 μl of each test serum diluted 1/6,400 was applied to each well of micro-titer plate wells sensitized with C. albicans cell wall mannan and the plate was incubated at 37°C for 1 h.
More importantly, the method developed in this work can also be applied to other fission materials for optimizing the design of fission sensitized photovoltaic devices.
14 Initially the patient is sensitized using a 2% solution of diphenylcyclopropenone applied to a 4 × 4 cm area of the scalp.
Hemin-mediated dimerization of p-hydroxybenzoic acid in the presence of H2O2 also generates a species capable of sensitizing Tb III)–EDTA, although this has not yet been applied to an immunoassay format [ 71].
Since Sal has been shown to sensitize resistant cancer cells or cancer stem cells, cotreatments using MK-2206 and Sal could also be applied to these cell types.
LEW rats were sensitized with 100 μL DNFB (1% (w/v) in 4 : 1 acetone : olive oil) applied to the skin of the shaved abdomen.
The mice were sensitized with 100 μl of 0.15 % DNFB in an acetone olive oil (3: 1) or a vehicle applied to the dorsal skin twice each week for six weeks.
To sensitize mice, 17 μL of 0.4% DNFB(Sigma) or 3% 4-ethoxymethylene-2-phenyl-2-oxalin-5-one (oxazolone, Sigma) solution in acetone:olive oil (4:1) was applied to the shaved abdomen on day 0 and 1.
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