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The same approach may not always be applied to medicinal products used to treat children.
Because both types of exposure involve trivalent arsenic and occur through the same mechanism of oral consumption followed by gastrointestinal absorption, it is possible that epidemiologic data from studies of drinking-water exposure may be applied to medicinal arsenic exposure.
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It is unclear for the moment in which way this provision shall be handled by the MSs as this also apply to medicinal products authorised before the entry into force of this Regulation.
This applies to medicinal herbal teas or homemade herb treatments as well.
The strategy used in the modeling work can be applied to other medicinal chemistry programs to help improve hERG profile.
The method could be applied to other medicinal plants contaminated with adulterants.
The Jaccard abundance-based similarity index (Chao et al. 2005) and the Sørensen similarity index based on species presence absence (Magurran 2004) were applied to quantify medicinal species turnover within forest-use types.
The methodological framework was built around three stages of the HTA process: (a) evidence, (b) its interpretation, and (c) its influence on the final recommendation; and was applied to two orphan medicinal products.
However, condom use for embryo-fetal risk from treatment of male subjects with investigational medicinal products only applies to investigational medicinal products with demonstrated or suspected human teratogenicity/fetotoxicity in early pregnancy at sub-therapeutic systemic exposure levels (not further specified).
The method was applied to detect methotrexate in medicinal tablets and spiked human blood serum samples.
Bitumen was also applied to the skin for medicinal purposes and during ritual practices and was used extensively in ancient Egyptian mummification processes (Harrell and Lewan 2002).
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