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Of note, different cut-offs may need to be applied to differing sub-types of invasive breast carcinomas to maximise the clinical benefit of determination of proliferation marker expression, which is unlikely to be a 'one size fits all'.
Says Herman W. Bevis, head partner at Price Waterhouse & Co., "A single accounting treatment applied to differing facts and circumstances can produce a lack of comparability just as surely as diverse accounting treatments applied to similar facts and circumstances".
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This was also the case for S3, the statistic sensitive to changes in shape, when applied to populations differing only in orientation.
The external validity of some of these multiparametric models for the prediction of preeclampsia has been evaluated in several recent studies, with algorithms applied to populations differing in ethnicity and background incidence of the disease.
Legislation on containment of dangerous pathogens (1 ) and measures applied to contacts differ among countries, sometimes with extreme consequences.
Table 12 shows the different acid leaching conditions that were applied to produce different catalysts with differing Si/Al ratios (acidity) based on the severity of acid leaching.
Computational fluid dynamics was applied to six different profiles with differing gap sizes.
The limitations of these models is that they are specific for only a single type or subtype of cancer, and may not be broadly applied to tumors of differing origins.
This approach can be readily applied to other traits differing among humans and/or higher primates and other species to aid in gene discovery.
In this work, proteomics and a complementary transcriptomic approaches were applied to two NILs differing for the presence of the highly effective broad spectrum Rph15 leaf rust resistance gene.
However, it is very likely that the conclusions can be generalized and also applied to other LPTCs differing in their preferred directions and receptive field location, since LPTCs can generally be assumed to receive input from the same type of local motion detectors and share similar spatial integration properties (e.g. Egelhaaf and Borst, 1993).
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CEO of Professional Science Editing for Scientists @ prosciediting.com