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Finally, knowledge derived from genes identified in invertebrates and from genetically engineered mice are applied to developmental issues of primate neurobiology in order to achieve a greater understanding of the evolutionary growth of the cerebral cortex as well as pathogenesis of a host of genetic and acquired cellular abnormalities of this structure in humans.
However, to improve our understanding of how specific leukaemogenic mutations corrupt entire transcriptional programmes, genome-wide studies need to be applied to developmental time-courses of leukaemogenesis.
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In addition, she suggested that neuropsychological dissociation studies of brain injuries and stroke patients that have dramatically influenced cognitive research may not apply to developmental disorders such as developmental dyscalculia.
However, the concept of redundancy can be applied to any developmental process where overlap between components of the developmental system can substitute for each other, potentially freeing one or more of the components to take on new functions.
The standardized Finnish version of Reynell Developmental Language Scales III, the Comprehension scale [ 38, 39] was applied to exclude developmental language disorders.
Then how behavioral-genetic methods are being applied to test developmental theory and to detect environmental causes of antisocial behavior is illustrated.
Suppressive subtractive hybridization (SSH) and differential display (DDRT) have been successfully applied to early developmental studies [ 20- 25].
This result suggests a more complex post-transcriptional regulation in the maternal stages since transcriptional regulation cannot be applied to control developmental processes prior to MZT.
Given the societal importance of risk assessments applied to potential developmental neurotoxicants, studies should be deemed questionable if they fail to include outcome measures based on sexual dimorphisms in nonreproductive behaviors.
A one-way ANOVA was applied to the developmental series using Welch's t-test (which does not assume equal variance) with P < 0.05 and the Benjamini-Hochberg false discovery rate multiple testing correction.
It remains to be assessed whether this mechanism we propose might also account for the formation of new grid representations in a novel environment the animal adapts to, for a sufficient time, or if, instead, it can only be applied to the developmental period.
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