The phrase "applied to a significant" is grammatically correct and can be used in written English.
It can be used in contexts where you are discussing something that has been implemented or utilized in relation to an important or noteworthy aspect.
Example: "The new policy was applied to a significant number of employees to ensure compliance with the updated regulations."
Alternatives: "implemented for a considerable" or "utilized in a major".
The identification methodology has been applied to a significant proportion of the Spanish main road network on selecting some 15 sections of historic roads of very different characteristics.
Although the number of genes we collected is limited in this study, we nonetheless observed common genetic features of these cis-regulatory genes that could be applied to a significant fraction of genes analyzed (21/26 in which the reported associations could be replicated).
With the new tax reform, Value Added Tax (VAT) will be applied to a significant number of basic consumer goods.
By requiring at least three subsequent visits in REM, and 24 weeks of observation time, it is unlikely that this limitation applied to a significant number of patients.
However we show here that the high-copy alleles characteristic of African populations are not necessarily simply related to the European alleles, and there is clearly a need for accessible physical remapping approaches that can be applied to a significant number of samples to fully characterise structural variation at this locus.
These guidelines apply to a significant proportion of VA ED users with common ambulatory conditions.
However, it need only apply to a significant fraction of genes in order to explain the correlation between expression level and evolutionary rate, which is far from perfect.
The International Convention on the Protection of the Rights of All Migrant Workers and Members of Their Families applies to a significant number of sex workers who travel between States to engage in sex work [ 5].
There are limitations of the study, such as the lack of information about the time between data collection periods, but if the results apply to a significant proportion of back pain patients, there are important clinical implications.
As a design matter, an SPOE strategy has much to recommend it as applied to a systemically important company with significant nonbank subsidiaries or significant foreign operations.
A significant branch move (or edit) is one that, when applied to a tree, causes a significant change in tree topology.
