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The overall response rate of 57 % and median PFS of 5.1 months obtained with the CC arm are consistent with those reported in our previous phase II study that applied the same regimen [ 7].
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These were blinded towards the index procedure and applied the same physiotherapeutic regimen to all patienets in the study.
This is in contrast to a previous clinical study in breast cancer patients that applied the same chemotherapy regimen and had very similar inclusion and exclusion criteria in which a higher incidence of FN in pegfilgrastim-treated patients (9% [7 of 80 patients]) was reported [ 2].
This is probably a result of the drug not receiving its license for use in PsA until 2004 and national guidelines not being issued until 2005, and thus most physicians may have applied the same dosing regimen used for RA to these patients.
The amount of pathophysiological impairment in patients with acute respiratory distress syndrome (ARDS) is variable and applying the same ventilator regimen to every patient is questionable.
Re-challenged mice were unable to reject a second 4T1 tumor; however 100%% of them could be totally cured by applying the same neoadjuvant combined regimen.
We also found that, although the combined therapy does not induce an efficient long-term protection against 4T1 tumors, 100%% of re-challenged mice could be totally cured by applying the same neoadjuvant combined regimen.
The same regimen applied to borderline patients resulted in a slightly longer neutropenia.
For control groups, the same regimen was applied using naïve rabbit serum.
The same regimen was applied during a direct exposure of endothelial cells to the stilbenes.
Now Ivory is on the same regimen.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com