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The degree to which these approaches can be applied relies on the level of information known about the originator and information that supports application of the originator model to the biosimilar.
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Therefore, as pointed out in [26], empirical methods are almost always applied, relying on the outputs of MCMC samplers and diagnostics computed from the produced sequence to check convergence.
The original MIMO problem is reduced to a set of SISO designs by applying an input decoupling that only relies on well known geometric properties as well as on the mass propertiesofthe spacecraft and the test masses.
Some mainstream economics is highly theoretical, though most of it is applied and relies on only rather rudimentary theory.
While the applied solution relies on a number of general assumptions, it has been found that reasonable comparison can be made to previously completed pulse interference and pumping tests.
The OPI clustering algorithm was then applied, which relies on knowledge such as Gene Ontology annotations to optimize cluster boundaries, normalization and weighting methods, so that the highest proportion of genes with particular classifications is contained in the smallest sized cluster of co-expressed genes.
Much of the analysis applied here relies on the assumption that the pneumococcal serotypes are homogeneous.
It is axiomatic that successful applied biology relies on sound taxonomy.
For characterizing a GitHub issue as a bug, we relied on the labels applied by the users.
The judge's carefully applied analysis, relying on principles set forth by the Supreme Court, provides a model for other courts faced with similar legal challenges.
The applied descriptors rely on the Kolmogorov Smirnov statistics, maximum subregions statistics, percolation theory, fractal texture analysis, and Haralick texture descriptors.
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CEO of Professional Science Editing for Scientists @ prosciediting.com