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The use of such novel designs for bioequivalence assessment can be applied for staged investments, particularly when there is uncertainty in formulation POS or when the pilot-scale pharmacokinetic studies are not likely to predict the final-scale pivotal studies.
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Iodine-124 has recently been applied for staging of differentiated thyroid cancer, as reported in a few case reports and small series, with promising results [ 17– 17].
We point out that this model cannot be directly applied for stage I and stage II GICs because there are no uncharged graphene layers, the charge transfer is much stronger and the line position is influenced by the Fano interference with the conduction electrons.
Once completed, the project team can apply for stage 2 funding (4 two-year grants of US$150,000) to pursue the research and adaptation needed.
The tournament will be hosted across 13 cities and the FAW has applied for group-stages matches and a last-16 tie at the Millennium Stadium.
Such profiling, however, has not yet been applied for earlier stages of human liver development, which are characterized by extensive cell proliferation as well as differentiation.
This reflects the fact that introduced changes were not applied for UICC stage I patients.
For ABCB1, a single split is observed, as illustrated in Fig. 4A, where ABCB1.S7 corresponds to rs2157926, and a cost complexity parameter (cp) of 0.01 is applied for first-stage pruning.
To better understand these combustion phases, chemiluminescence spectroscopy and chemical-kinetic analysis were applied for the single-stage ignition fuel, iso-octane, and the two-stage fuel, PRF80.
Scaling rules were applied for the late stages to show serious deviations from theoretical expectations.
Taguchi method was applied for the roughing stage to optimize the polishing conditions for the best material removal rate.
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