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We identified singletons (and private doubletons) from each WGS dataset and applied filters to extract those used for inferring SDS.
As data are manipulated via filtering, binning, region selection, plotting, and fitting, filtwin iteratively notes the various applied filters, in essence recording ''the state of your data".
Cancer-active compounds exist in a much greater volume of space than generic hit-like space and most of them fail the commonly applied filters for orally bioavailable drugs.
Only data points that pass all currently applied filters are exported, and only variables which are currently displayed on the Dashboard are represented in the exported data file.
We also applied filters for sequence quality based on the quality scores provided by the Illumina base calling software.
Prior to assembly and mapping (described below), we applied filters to remove low quality reads and reads containing suspected poly-Adenine tails from all three paired-end lanes.
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At each stage, we applied filtering criteria selected to retain informative gene families and trees.
Thus, with applied filtering, the PIN became progressively disintegrated.
A moderately smoothing filter was applied (filter B) on all CT systems.
This is a further clear evidence of the selectivity of the applied filter times.
A commonly applied filter of 8 mm FWHM (full-width at half maximum) was used.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com